| Ingenuity canonical pathways | value | Affected molecules |
| Role of macrophages, fibroblasts, and endothelial cells in rheumatoid arthritis | 1.15E−04 | TLR2, IL1R2, SOCS3, WNT10A, STAT3, IL17RA, and IRAK2 | Inhibition of matrix metalloproteases | 4.07E−04 | MMP7, TIMP1, and A2M | IL-6 signalling | 9.12E−04 | IL1R2, SOCS3, STAT3, and A2M | IL-10 signalling | 2.04E−03 | IL1R2, SOCS3, and STAT3 | Growth hormone signalling | 2.14E−03 | SOCS3, STAT3, and A2M | IL-22 signalling | 3.55E−03 | SOCS3, STAT3 | Role of JAK family kinases in IL-6-type cytokine signalling | 3.89E−03 | SOCS3, STAT3 | IL-9 signalling | 6.31E−03 | SOCS3, STAT3 | Role of JAK2 in hormone-like cytokine signalling | 7.41E−03 | SOCS3, STAT3 | Tetrahydrobiopterin biosynthesis I | 1.10E−02 | GCH1 |
|
|