Racial Differences in Expression Levels of miRNA Machinery-Related Genes, Dicer, Drosha, DGCR8, and AGO2, in Asian Korean Papillary Thyroid Carcinoma and Comparative Validation Using the Cancer Genome Atlas
Table 3
Correlation of the clinicopathological parameters with Dicer, Drosha, AGO2, and DGCR8 mRNA expression levels in white American patients of the TCGA.
Dicer
P
Drosha
P
DGCR8
P
AGO2
P
Low
High
Low
High
Low
High
Low
High
Age
0.921
0.641
0.877
0.507
<40
9
7
10
6
8
8
11
5
41–50
5
3
3
5
3
5
4
4
>50
4
3
4
3
4
3
4
3
Histologic Stage
0.901
0.743
0.595
0.434
(i)
13
8
12
9
10
11
14
7
(ii)
2
3
2
3
2
3
2
3
(iii)
2
2
3
1
2
2
3
1
(iv)
1
0
0
1
1
0
0
1
T stage
0.689
0.444
0.489
0.187
(1)
5
2
4
3
3
4
3
4
(2)
7
6
8
5
6
7
7
6
(3)
5
5
5
5
5
5
9
1
(4)
1
0
0
1
1
0
0
1
N stage
1.000
0.269
0.143
0.264
(+)
9
6
7
8
9
6
11
4
(−)
9
6
10
5
5
10
7
8
M stage
1.000
0.433
1.000
0.414
(+)
1
0
0
1
1
0
0
1
(−)
16
12
17
12
14
14
17
11
Multifocality
0.621
0.607
1.000
0.605
(+)
3
1
3
1
2
2
3
1
(−)
15
12
14
13
13
14
16
16
Linear by linear association. Chi-squared test. Fisher’s Exact test.
