A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density

Figure 2

Regional association plots for the lumbar spine BMD in the HDAC9 and SHFM1 chromosomal regions. The x-axis is the physical position on the chromosome (Mb), and the y-axis denotes the association test result as the −log ( value). SNPs are color-coded according to the linkage disequilibrium (LD) with the lead SNP (purple diamond) indicated by the arrow. (a) The SNP rs11764843 in the HDAC9 region; (b) the SNP rs17413103 in the SHFM1 region. The regional association plots were generated using LocusZoom and only show genotyped SNPs.

(a)

(b)