MicroRNAs as Biomarkers in Thyroid Carcinoma

Table 3

Circulating miRNAs as diagnostic biomarkers in thyroid carcinoma.

Histotype	Sample type	miRNA	Up/downregulated	Reference
PTC	Serum	let-7e, 151-5p, 222	Up	[75]
	Plasma	146b, 222	Up	[76]
	Serum	190	Up	[77]
		95	Down
	Plasma	hsa-let7b-5p, hsa-miR-10a-5p, hsa-miR-93-5p, hsa-miR-191	Up	[78]
		hsa-miR-146a-5p, hsa-miR-150-5p, hsa-miR-199b-3p, has-miR-342-3p	Down
	Plasma	let-7i, 25-3p, 140-3p, 451a	Up	[79]
	Plasma	146b, 155	Up	[80]
	Plasma-derived exosomes	31-5p, 126-3p, 145-5p, 181a	Up	[81]
	Plasma	9-3p, 124-3p	Up	[82]
	Serum	222	Up	[83]
		21	Down
	Serum	24-3p, 28-3p, 103a-3p, 146a-5p, 146b-5p, 191-5p, 221-3p, 222-3p	Up	[84]
FTC	Plasma-derived exosomes	21	Up	[81]

FTC: follicular thyroid carcinoma; PTC: papillary thyroid carcinoma.