Research Article

Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans

Table 3

Specific enzyme activities and sterol contents of the cultures.

CulturesNR (mkat/kg protein)G6PDH (mkat/kg protein)GR (mkat/kg protein)GPx (mkat/kg protein)Catalase (kat/kg protein)Sterol content (μg/mg)

Control strain untreated2.6 ± 0.38.0 ± 13.8 ± 0.50.40 ± 0.040.20 ± 0.025.8 ± 0.6
Control strain MSB1.6 ± 0.38.5 ± 14.8 ± 0.60.51 ± 0.050.38 ± 0.035.7 ± 0.2
Control strain tBOOH0.3 ± 0.18.3 ± 0.94.4 ± 0.60.57 ± 0.050.40 ± 0.033.3 ± 0.2
Control strain diamide0.6 ± 0.17.8 ± 14.5 ± 0.50.77 ± 0.080.30 ± 0.037.0 ± 0.7
ΔatfA strain untreated2.8 ± 0.37.4 ± 0.93.4 ± 0.40.33 ± 0.040.18 ± 0.026.8 ± 0.7
ΔatfA strain MSB3.1 ± 0.48.0 ± 14.6 ± 0.50.46 ± 0.050.43 ± 0.045.7 ± 0.4
ΔatfA strain tBOOH0.3 ± 0.17.7 ± 0.84.8 ± 0.50.58 ± 0.060.44 ± 0.042.7 ± 0.2
ΔatfA strain diamide0.7 ± 0.18.1 ± 1.24.6 ± 0.40.44 ± 0.050.43 ± 0.047.3 ± 0.3

Mean ± S.D. values are presented. Significantly different from the value measured in the appropriate untreated cultures according to Student’s t-test (, ).