Association of PTPN22 Haplotypes (−1123G>C/+1858C>T) with Rheumatoid Arthritis in Western Mexican Population

Table 2

Association analyses of the PTPN22 haplotypes constructed for the −1123G>C and +1858C>T SNPs in RA patients and CS.

Haplotypes −1123G>C/+1858C>T	RA ()%	CS ()%	OR	(95% CI)	p
GC	66.26	63.33	NA	NA	NA
CC	28.18	34.44	0.78	(0.62–0.99)	0.05
CT	5.15	2.22	2.18	(1.15–4.16)	0.01
GT	0.40	0	6.69	(0.34–130.09)	0.25

Values represent a frequency of cases with respect to total number of haplotypes, for RA patients and control subject. SNP: single nucleotide polymorphism; RA: rheumatoid arthritis; CS: control subjects; OR: odds ratios; CI: confidence intervals; level of significance for Fisher exact test; NA: not applicable.