The β-Lactamase Gene Profile and a Plasmid-Carrying Multiple Heavy Metal Resistance Genes of Enterobacter cloacae

Table 3

The MIC values of antibacterial drugs for the strains (μg/mL).


Strains	AMP	KAN	CAZ	CTX	CPZ	CMN	CEF	CFZ	FOX	CRO	ATM	PRL	PTZ	IMC

ATCC25922	4	2	0.25	0.0625	0.125	1	0.125	2	4	0.0313	0.125	2	4	0.25
BL21	0.5	4	0.0625	0.0156	0.0156	1	0.0313	2	2	0.0156	0.0156	0.5	0.5	0.5
pET-28a/BL21	0.5	32	0.0625	0.0156	0.0156	1	0.0313	2	2	0.0156	0.0156	0.5	0.5	0.5
CG34	256	0.5	0.125	0.125	0.0625	1024	0.0625	512	1024	0.0313	0.25	2	2	4
Y490	256	2	0.5	0.25	1	>1024	0.125	512	1024	0.5	0.0313	2	4	2
CG76	>1024	8	128	128	64	1024	16	>1024	1024	512	32	512	32	8
Y546	512	2	2	1	2	>1024	0.25	1024	1024	2	1	8	8	4
CG85	>1024	4	1	1	1	>1204	0.25	1024	>1024	1	0.25	4	4	4
Y482	64	2	0.25	0.125	0.25	1024	256	512	0.0625	0	0.125	2	2	0.5
pET-28a-bla_MIR (CG34)/BL21	128	64	4	4	1	32	0.125	256	32	4	1	8	8	1
pET-28a-bla_MIR (Y490)/BL21	128	64	4	4	0.5	32	0.0625	256	32	4	1	8	4	1
pET-28a-bla_MIR (CG76)/BL21	128	64	4	4	1	32	0.0313	256	32	4	1	8	4	1
pET-28a-bla_MIR (Y546)/BL21	128	64	4	4	1	32	0.0625	256	32	4	1	8	8	1
pET-28a-bla_MIR (CG85)/BL21	128	64	4	4	1	32	0.125	256	32	4	1	8	8	1
pET-28a-bla_MIR (Y482)/BL21	128	64	4	4	1	32	0.125	256	32	4	1	8	8	1
pET-28a-bla_CTX-M-9a/BL21	8	64	0.25	4	1	4	0.03	64	4	0.03	0.03	2	1	1
pET-28a-bla_SHV-12/BL21	8	64	2	4	1	4	0.25	64	4	0.03	0.03	32	2	2

IPTG was added to a final concentration of 1 mmol/L to standard Mueller-Hinton (M-H) agar plates. All MIC determinations were performed by agar dilution assays. FOX: cefoxitin; CAZ: ceftazidime; CTX: cefotaxime; AMP: ampicillin; KAN: kanamycin; CPZ: cefoperazone; CMN: cefminox; CEF: cefoselis; CFZ: cefazolin; CRO: ceftriaxone; ATM: aztreonam; PRL: piperacillin; PTZ: piperacillin/tazobactam; IMC: imipenem/cilastatin sodium hydrate.

International Journal of Genomics

The β-Lactamase Gene Profile and a Plasmid-Carrying Multiple Heavy Metal Resistance Genes of Enterobacter cloacae

Table 3