Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma
Table 1
Patient characteristics.
ID
Sex
Age
Tumor size (cm)
HIC characteristics
PASS score
N47
F
63
5.0
Ki-67 2.4%
n.a.
N49
M
65
4.0
Positive staining for synaptophysin. Ki-67 3.2%
3
N50
M
36
4.0
Positive staining for synaptophysin. S100 protein-positive sustentacular cells. Ki-67 2.2%
3
N51
M
46
1.5
Positive staining for chromogranin A and synaptophysin. S100 protein-positive sustentacular cells. Negative staining for c-kit, EGFr, p53. Ki-67 0.5%
2
N52
M
47
3.5
Positive staining for chromogranin A and synaptophysin. S100 protein-positive sustentacular cells. Negative staining for CD10. Ki-67 0.1%
4
N53
F
58
5.4
Ki-67 1.8%
5
N54
F
46
6.0
Positive staining for chromogranin A and synaptophysin. S100 protein-positive sustentacular cells. Focal positive staining for CD10. Ki-67 0.4%
6
N55
F
30
6.0
Positive staining for chromogranin A and synaptophysin. S100 protein-positive sustentacular cells. Ki-67 0.1%
4
N56
M
41
1.7
Positive staining for synaptophysin. S100 protein-positive sustentacular cells. Negative staining for calretinin. Ki-67 2.2%
2
N57
M
35
8.0
Positive staining for chromogranin A and synaptophysin. Few S100 protein-positive sustentacular cells. Negative staining for calretinin and α-inhibin. Ki-67 5.7%
4
N62
M
59
3.0
Ki-67 1.4%.
5
N63
M
26
7.0
Positive staining for synaptophysin. S100 protein-positive sustentacular cells. Negative staining for calretinin, MEL-A, and α-inhibin. Ki-67 4%
