Expanding the miRNA Transcriptome of Human Kidney and Renal Cell Carcinoma

Figure 2

Differential expression of previously unannotated miRNAs between nonmalignant and ccRCC samples. (a) Pie chart representing the proportion of miRNAs that are significantly differentially expressed between the samples. (b) Normalized expression of the previously unannotated miRNA Knm3_1968 in individual nonmalignant (green) and ccRCC samples (purple). (c) Normalized expression of Knm22_2209 in individual nonmalignant (green) and ccRCC samples (purple). (d) Normalized expression of Knm17_1130 in individual nonmalignant (green) and ccRCC samples (purple). (e) Summary of differential expression results for each previously unannotated miRNA. BHC-p represents the corrected value for the differential expression calculated using Student’s -test and Benjamini-Hochberg multiple correction analysis.

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