Research Article

Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

Table 4

Effect of mouse Cbs genotype on the solubility of total hair keratin.

Genotype ()Total SDS-soluble keratin, relative values ()
Hair stored at −80°CHair stored at 25°C, 6 months

Cbs−/− (5–8)1.17 ± 0.11 (8)1.51 ± 0.14 (5)
Cbs+/+ (5–8)1.18 ± 0.11 (8)2.22 ± 0.05 (5)
value0.8424.2 × 10−6