Differential Expression Profiling of Long Noncoding RNA and mRNA during Osteoblast Differentiation in Mouse

Figure 5

Global expression patterns of lncRNAs at the nine time points of osteoblast differentiation. (a) Hierarchical clustering of lncRNAs across the stages of osteoblast differentiation. (b) Number of lncRNAs showing up- or downregulation during osteoblast differentiation (fold change ≥ 2 or ≤0.5, FDR < 0.05). (c) Principal component analysis (PCA) of 3948 time series lncRNA expression profiles for different samples (three replicates for each time point of osteoblast differentiation).

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