Whole-Exome Sequencing Identifies One De Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder

Table 2

List of final candidate variants.

Genomic coordinates	Genotype				AA change	Gene	MAF		Functional prediction
	2.III-2	2.III-3	2.II-2	2.I-2			1 kG (ASN)	Thai	SIFT	Polyphen2 HumVar	MutationTaster
Chr2: 88876094	C/T	C/T	C/C	C/C	p.Glu672Lys	EIF2AK3	0.02	0.0067	Tolerated	Benign	Disease causing
Chr12: 95531341	C/T	C/T	C/C	C/C	p.Cys984Tyr	FGD6	0	0	Tolerated	Probably damaging	Disease causing
Chr14: 21861835	C/T	C/T	T/T	T/T	p.Asp2040Gly	CHD8	0.02	0.0067	Tolerated	Benign	Disease causing

Genotypes in this table are FWD genotype while genotypes in HGVS are REV genotype.