Changes in miRNA Gene Expression during Wound Repair in Differentiated Normal Human Bronchial Epithelium

Table 2

The results of pathway analysis of predicted target genes for profile 9 in DAVID database.

Category	Pathway	Enrichment score	No. of genes		(FDR corrected)
KEGG	Pathways in cancer	1.4	259	5.70E − 17	1.40E − 13
KEGG	PI3K-Akt signaling pathway	1.4	221	1.90E − 12	2.60E − 09
KEGG	MAPK signaling pathway	1.5	170	7.80E − 12	1.00E − 08
KEGG	Focal adhesion	1.5	141	3.40E − 11	4.50E − 08
KEGG	Axon guidance	1.6	92	1.50E − 09	2.00E − 06
KEGG	Ras signaling pathway	1.4	146	7.30E − 09	9.70E − 06
KEGG	cGMP-PKG signaling pathway	1.5	111	3.90E − 08	5.20E − 05
KEGG	Rap1 signaling pathway	1.4	135	4.50E − 08	6.00E − 05
KEGG	Proteoglycans in cancer	1.4	129	7.00E − 08	9.40E − 05
KEGG	FoxO signaling pathway	1.5	92	1.00E − 07	1.40E − 04
KEGG	Regulation of actin cytoskeleton	1.4	133	3.10E − 07	4.10E − 04
KEGG	Signaling pathways regulating pluripotency of stem cells	1.5	94	3.70E − 07	4.90E − 04
KEGG	T cell receptor signaling pathway	1.6	73	3.90E − 07	5.30E − 04
KEGG	Adrenergic signaling in cardiomyocytes	1.5	97	5.00E − 07	6.60E − 04
KEGG	Melanoma	1.7	54	5.00E − 07	6.70E − 04
KEGG	cAMP signaling pathway	1.4	125	6.50E − 07	8.70E − 04
KEGG	Glutamatergic synapse	1.5	78	1.40E − 06	1.90E − 03
KEGG	Wnt signaling pathway	1.4	91	1.90E − 06	2.60E − 03
KEGG	HTLV-I infection	1.3	154	2.10E − 06	2.80E − 03
KEGG	Dopaminergic synapse	1.5	85	2.90E − 06	3.90E − 03
KEGG	Renal cell carcinoma	1.7	49	3.00E − 06	3.90E − 03
KEGG	Neurotrophin signaling pathway	1.5	80	4.70E − 06	6.30E − 03
KEGG	TNF signaling pathway	1.5	72	5.70E − 06	7.60E − 03
KEGG	ErbB signaling pathway	1.5	61	7.30E − 06	9.80E − 03
KEGG	Sphingolipid signaling pathway	1.4	79	1.10E − 05	1.50E − 02
KEGG	Prostate cancer	1.5	61	1.30E − 05	1.70E − 02
KEGG	Insulin signaling pathway	1.4	88	2.10E − 05	2.80E − 02
KEGG	Inflammatory mediator regulation of TRP channels	1.5	66	2.30E − 05	3.00E − 02
KEGG	Dorsoventral axis formation	2	24	2.30E − 05	3.10E − 02
KEGG	Pancreatic cancer	1.6	47	3.00E − 05	4.10E − 02
KEGG	Glioma	1.6	47	3.00E − 05	4.10E − 02
KEGG	Oxytocin signaling pathway	1.4	98	3.50E − 05	4.70E − 02
KEGG	Platelet activation	1.4	83	3.50E − 05	4.70E − 02
KEGG	Insulin resistance	1.4	71	3.60E − 05	4.80E − 02

Number of predicted target genes that are involved in the particular pathway.