Table 2: Significantly enriched KEGG pathways among upregulated and downregulated genes in ischemic heart. The pathways are ranked according to the order of the increasing values. Gene count referred to the number of genes among all the pathway member genes.

KEGG pathway ID and nameGene count value

Upregulatedrno04610: complement and coagulation cascades114.59E − 07
rno04670: leukocyte transendothelial migration90.001
rno05322: systemic lupus erythematosus80.001
rno04510: focal adhesion110.003
rno04512: ECM-receptor interaction70.004
rno05200: pathways in cancer140.005
rno05414: dilated cardiomyopathy70.006

Downregulatedrno00071: fatty acid metabolism67.55E − 05
rno00280: valine, leucine, and isoleucine degradation61.18E − 04
rno00620: pyruvate metabolism57.45E − 04
rno03320: PPAR signaling pathway69.11E − 04
rno00330: arginine and proline metabolism40.018834
rno00020: citrate cycle (TCA cycle)30.04066
rno05412: arrhythmogenic right ventricular cardiomyopathy40.044529
rno00640: propanoate metabolism30.048358
rno00071: fatty acid metabolism67.55E − 05
rno00280: valine, leucine, and isoleucine degradation61.18E − 04