Research Article

−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children

Table 3

Prediction of the binding of the transcription factor to the promoter region of the TRPC6 gene with or without the −254C>G SNP.

GroupsTranscription factorScoreStartStopPredicted site sequence

LUC3-W///CCGGGGTCTCCTCGG
LUC3-MRELA11.833−256 bp−241 bpCGGGGGTCTCCTCGG
RELA11.349−256 bp−242 bpCGGGGGTCTCCTCG
RELA11.136−254 bp−244 bpCGGGGGTCTCCT

Note: the sections in italic font indicate the −254C or G allele.