Genus-Wide Comparative Genomics Analysis of Neisseria to Identify New Genes Associated with Pathogenicity and Niche Adaptation of Neisseria Pathogens

Figure 2

Phylogenetic analysis of Neisseria strains included in this study. (a) Phylogenetic tree of 107 Neisseria strains constructed by neighbour joining (NJ) approach using 16s rRNA genes with the Kimura 2-parameter substitution model, bootstrapped ×1000 replicates. Staphylococcus aureus subsp. aureus NCTC 8325 and Streptococcus dysgalactiae subsp. equisimilis AC-2713 were used as outgroups. Approval values of each major node were indicated. The subtree of N. meningitidis was compressed and denoted in purple. (b) Phylogenetic tree constructed by a maximum likelihood (ML) approach using concatenated single-copy gene dataset, bootstrapped ×100 replicates. Approval values of each major node were indicated. The subtree of N. meningitidis was compressed and denoted in purple.

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