Florfenicol Resistance in Enterobacteriaceae and Whole-Genome Sequence Analysis of Florfenicol-Resistant Leclercia adecarboxylata Strain R25

Table 4

MICs of antibiotics for the L. adecarboxylata R25 strain and its derivatives (μg/mL).

Strain	FFC	CHL	RIF	AMK	GEN	STR	SPE	KAN	NEO	NAL	NOR	CIP
L. adecarboxylata R25	128	128	256	2	0.125	8	64	4	0.5	8	1	0.25
pMD™19-T-aac(6)-Ib-cr/E. coli DH5α	8	8	16	16	0.25	4	8	64	2	4	0.13	<0.03
pMD™19-T-aadA16/E. coli DH5α	8	8	16	2	0.25	>64	>64	1	2	4	<0.03	<0.03
pMD™19-T-arr-3/E. coli DH5α	8	8	512	2	0.25	4	8	1	2	4	<0.03	<0.03
pMD™19-T-qnrB6/E. coli DH5α	8	8	16	2	0.25	4	8	1	2	32	0.25	0.25
pMD™19-T-floR/E. coli DH5α	64	32	16	2	0.25	4	8	2	2	4	<0.03	<0.03
E. coli DH5α	8	8	32	2	0.25	4	8	1	2	4	0.06	<0.03
E. coli ATCC25922	4	4	8	4	0.5	8	8	4	2	2	<0.03	<0.03

Abbreviations: FFC: florfenicol; CHL: chloramphenicol; RIF: rifampin; AMK: amikacin; GEN: gentamicin; STR: streptomycin; SPE: spectinomycin; KAN: kanamycin; NEO: neomycin; NAL: nalidixic acid; NOR: norfloxacin; CIP: ciprofloxacin.