The Necessity of Prenatal Diagnosis by CMA for the Women with NIPS-Positive Results

Table 2

The results of prenatal diagnosis in the pregnant women with NIPS-positive results.

Group		Prenatal diagnosis	Chromosome abnormalities		CNVs					Polymorphism
			Aneuploidy	Structural abnormalities	P	LP	VUS	LB	B
NIPS reported as T21/T18/T13 positive	428	385	305	23	0	0	0	0	0	0
NIPS reported as SCA positive	411	265	71	13	1	0	6	0	0	4
NIPS reported as other chromosome aneuploidy positive	124	67	0	3	2	0	5	3	0	0
NIPS reported as chromosome signal reduction	56	44	0	0	0	0	4	0	0	1

CNVs: copy number variations; P: pathogenic; LP: likely pathogenic; VUS: variants of uncertain significance; LB: likely benign; B: benign. The detailed results are shown in Supplementary table 1.