Research Article
The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001
Table 2
DEGs related to estrogen degradation by R-001under different estrogen treatment conditions.
| | Gene ID | Gene name | Description | Log2(FC) | | G vs. E1 | G vs. E2 | G vs. EE2 |
| | C7H75_RS21980 | 17β-HSD | 17beta-estradiol 17-dehydrogenase | —a | 13.60 | 13.41 | | C7H75_RS02785 | kshA | 3-ketosteroid-9-alpha-hydroxylase oxygenase subunit | 14 | 12.4 | 12.8 | | C7H75_RS08645 | kshA | 3-ketosteroid-9-alpha-hydroxylase oxygenase subunit | — | 11.71 | — | | C7H75_RS18910 | kshB | 3-ketosteroid-9-alpha-hydroxylase reductase subunit | — | — | 1.03 | | C7H75_RS04150 | tesI | 3-oxo-5alpha-steroid 4-dehydrogenase | — | 10.91 | 11.95 | | C7H75_RS24110 | ksdI | Steroid Delta-isomerase | — | 14.33 | 14.42 | | C7H75_RS03705 | fadD3 | AMP-binding enzyme | 2.76 | — | 1.89 | | C7H75_RS25395 | hsaC | Glyoxalase | — | 6.02 | 12.88 | | C7H75_RS00645 | hsaD | Alpha/beta hydrolase | — | 11.83 | — | | C7H75_RS02355 | hsdA | Short-chain dehydrogenase/reductase | — | 13.11 | 12.36 |
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aNo significant differential expression in this treatment group.
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