Identification of Circulating Exosomal miR-101 and miR-125b Panel Act as a Potential Biomarker for Hepatocellular Carcinoma

Table 1

miR-101 pathway.

KEGG	kegg_dscp	Gene	value	Possibility
ko05218	Melanoma	IGF1R, CCND1, CDKN1A, NRAS, MET, MAP2K1, CDK6, MITF		0.017683847
ko05211	Renal cell carcinoma	MET, JUN, RAC1, NRAS, RAP1B, VHL, MAP2K1, CRK, EP300, PAK3		0.015166268
ko05210	Colorectal cancer	TGFBR2, TGFBR1, CASP3, RAC1, CCND1, BIRC5, FOS, JUN, GSK3B, MAP2K1, RHOA, MSH2		0.025836046
ko04115	p53 signaling pathway	CCND2, CASP3, CDK1, CCND1, CDKN1A, ATM, CCNG1, ZMAT3, PPM1D, RRM2, CDK6		0.014138969
ko05220	Chronic myeloid leukemia	TGFBR2, TGFBR1, CCND1, CDKN1A, NRAS, MAP2K1, RUNX1, CDK6, CRK		0.010847935
ko04520	Adherens junction	TGFBR2, IGF1R, TJP1, SSX2IP, RAC1, VCL, PTPRJ, FYN, TGFBR1, MAP3K7, PVRL1, MET, PVRL2, NLK, PTPN1, EP300, RHOA		0.039034869

The detailed miR-101 pathway was associated with different cancers and signaling pathways and their targeted genes based on the TCGA database.