Genomics technologies have been widely applied to biomedical research. Taking advantage of emerging genomics technologies such as next generation sequencing (NGS), researchers could dive into detection and quantification of more aboard genomic elements (i.e., DNA, mRNA, miRNA, cirRNA, and lncRNA) to uncover the underlying diseases etiology and pathology. Furthermore, some findings and observations from the genomics space have successfully demonstrated the potential application to drug development.

We invite investigators to contribute original research articles as well as review or opinion articles that seek to address how the genomics advance drug development regarding efficacy, safety, and personalized design. A particular interest will be given to papers exploring or discussing the application of different genomic techniques such as RNAseq, DNAseq, and Mirseq to facilitate NGS-driven drug development.

Potential topics include but are not limited to the following:

• Application of RNAseq/DNAseq/Mirseq for drug safety evaluation and biomarker discovery
• Importance and significance of genomics for rare diseases and cancers
• Uncovering molecular and cellular mechanism of drug induced toxicity with genomics technology
• Integrated analysis of genomics data to address biomedical questions
• Bioinformatics methodologies and pipelines for genomics data analysis
• Analyses related to the safety assessment of drug carriers