Correlation of Chimerism with Acute Graft-versus-Host Disease in Rats following Liver Transplantation
Figure 4
Changes of chimerism levels after liver transplantation. PBMC chimerism following sex-mismatched liver transplantation was identified by real-time PCR based on a rat Y-chromosome-specific primer, as described in Materials and Methods (Section 2). As described in Materials and Methods (Section 2), group 1 (white bars) received syngeneic liver transplantation, group 2 (gray bars) received semiallogeneic liver transplantation without splenocyte transfusion, and group 4 received semiallogeneic liver transplantation together with the transfusion of splenocytes. Each group consisted of 6 animals. *, + (compared with groups 1 and 2).