Etiopathogenesis of Nonalcoholic Steatohepatitis: Role of Obesity, Insulin Resistance and Mechanisms of Hepatotoxicity

Figure 3

Development and progression of nonalcoholic fatty liver disease.  Abbreviations: tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), I-kappa-B-kinase-β (IKKβ), nuclear-factor-kappa-B (NF-κB), Jun N-terminal kinase (JNK), and free fatty acids (FFAs).