International Journal of Hepatology / 2012 / Article / Tab 2

Clinical Study

Milan Criteria and UCSF Criteria: A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States

Table 2

Comparison of patient characteristics by transplant criteria.



Factors
Transplant criteria
Milan UCSF
P value
(N = 1913 )(N = 59)

Age (yrs)
 Mean, ± SEM 56.2 ± 0.1858.4 ± 1.02
 ≤50 426 (22%) 11 (19%) 0.11
 51–64 1169 (61%) 32 (54%)
 ≥65 318 (17%)16 (27%)
Gender 0.87
 Female 399 (21%) 13 (22%)
 Male1514 (79%)46 (78%)
Diabetes mellitus 0.47
 No 1418 (75%) 43 (77%)
 Yes*465 (25%)13 (23%)
BMI 0.59
 Mean, ±SEM 28.1 ± 0.1128.4 ± 0.66
Liver directed therapy <0.001
 No 1243 (65%) 23 (39%)
 Yes670 (35%)36 (61%)
Number of tumors <0.001
 1 1316 (69%) 23 (39%)
 2 420 (22%) 26 (44%)
 3177 (9%)10 (17%)
Vital status 0.37
 Alive 1426 (74%) 41 (70%)
 Dead487 (26%)18 (30%)
Hepatitis C Virus 0.45
 Negative 615 (36%) 20 (42%)
 Positive1094 (64%)28 (58%)
Hepatitis B Virus 0.88
 Negative 1073 (63%) 30 (61%)
 Positive639 (37%)19 (39%)
Total Tumor Diameter <0.001
 Mean ± SEM3.27 ± 0.035.86 ± 0.09
COD 0.01
 Malignancy recurrence 149 (35%) 9 (69%)
 Other278 (65%)4 (31%)

*Yes: type I or II; or type unknown.
SEM: standard error of the mean; BMI: body mass index; COD: cause of death.

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