Review Article

Experience Since MELD Implementation: How Does the New System Deliver?

Table 1

Standard MELD exceptions in Germany and their adjusted MELD score or adjusted 3-months-mortality, respectively [3].

DiseaseInitial match MELD/adjusted 3-month mortality

Hepatocellular carcinoma (HCC)15%
HepatoblastomaMELD 30
Polycystic liver disease10%
Hyperoxaluria type 110%
Persisting dysfunction following OLT
(including “small-for-size”)
Current lab MELD  plus
20%
Cystic fibrosis10%
Familial amyloid polyneuropathy (FAP)15%
Hepatopulmonary syndrome15%
Portopulmonary hypertension (POPH)25%
Urea cycle disordersMELD 30
Morbus Osler15%
Hepatic epithelioid hemangioendothelioma (HEHE)15%
Biliary sepsis/secondary sclerosing cholangitis (SSC)Current lab MELD  plus
30%
Primary sclerosing cholangitis (PSC)15%
Cholangiocarcinoma10%