Table of Contents Author Guidelines Submit a Manuscript
International Journal of Hepatology
Volume 2012, Article ID 265305, 9 pages
Research Article

Paraoxonase Activity and Expression Is Modulated by Therapeutics in Experimental Rat Nonalcoholic Fatty Liver Disease

1Internal Medicine Department A, Ziv Medical Center, Safed 13100, Israel
2Faculty of Medicine, Bar-Ilan University, 13100 Safed, Israel
3Oncology Unit, Ziv Medical Center, Safed 13100, Israel
4Pathology Department, Ziv Medical Center, Safed 13100, Israel
5Biotechnology Department, Ort Braude College of Engeneering, Karmiel 21982, Israel
6The Lipid Research Laboratory, Technion Faculty of Medicine, The Rappaport Family Institute for Research in the Medical Sciences and Rambam Medical Center, Haifa 31096, Israel

Received 11 November 2011; Revised 16 January 2012; Accepted 23 January 2012

Academic Editor: Manuela Neuman

Copyright © 2012 O. Hussein et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Anabel García-Heredia, Elizabeth Kensicki, Robert P. Mohney, Anna Rull, Iris Triguero, Judit Marsillach, Carmen Tormos, Bharti Mackness, Michael Mackness, Diana M. Shih, Juan Pedro-Botet, Jorge Joven, Guillermo Sáez, and Jordi Camps, “Paraoxonase-1 Deficiency Is Associated with Severe Liver Steatosis in Mice Fed a High-fat High-cholesterol Diet: A Metabolomic Approach,” Journal of Proteome Research, vol. 12, no. 4, pp. 1946–1955, 2013. View at Publisher · View at Google Scholar
  • K Üstün, S Taysı, U Sezer, E Demir, E Baysal, T Demir, E Sarıçiçek, H Alkış, Sz Şenyurt, M Tarakçıoğlu, and N Aksoy, “ Radio-protective effects of Nigella sativa oil on oxidative stress in tongue tissue of rats ,” Oral Diseases, vol. 20, no. 1, pp. 109–113, 2013. View at Publisher · View at Google Scholar
  • Y. Atamer, N. Yenice, N. Ilhan, A. Atamer, A. S. Can, A. Hekimoglu, and Y. Kocyigit, “Effects of rosiglitazone on serum paraoxonase activity and metabolic parameters in patients with type 2 diabetes mellitus,” Brazilian Journal Of Medical And Biological Research, vol. 46, no. 6, pp. 528–532, 2013. View at Publisher · View at Google Scholar
  • Oztekin Cikman, Adile Ozkan, Adem Bozkurt Aras, Omer Soylemez, Hilal Alkis, Seyithan Taysi, and Muammer Karaayvaz, “Radioprotective Effects of Nigella Sativa Oil Against Oxidative Stress in Liver Tissue of Rats Exposed to Total Head Irradiation,” Journal of Investigative Surgery, pp. 140328105713005, 2014. View at Publisher · View at Google Scholar
  • Gaili Chen, Julien Broséus, Sébastien Hergalant, Audrey Donnart, Catherine Chevalier, Francisco Bolaños-Jiménez, Jean-Louis Guéant, and Rémi Houlgatte, “Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: Relevance to nonalcoholic liver disease,” Molecular Nutrition & Food Research, 2014. View at Publisher · View at Google Scholar
  • Osamah Hussein, Lidia Izikson, Yunis Bathish, Enas Dabur, Alaa Hanna, and Jamal Zidan, “Anti-atherogenic properties of high-density lipoproteins in psychiatric patients before and after two months of atypical anti-psychotic therapy,” Journal Of Psychopharmacology, vol. 29, no. 12, pp. 1262–1270, 2015. View at Publisher · View at Google Scholar
  • Gehan H. Heeba, and Mohamed A. Morsy, “Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease,” Environmental Toxicology and Pharmacology, vol. 40, no. 3, pp. 907–914, 2015. View at Publisher · View at Google Scholar
  • Anabel García-Heredia, Marta Riera-Borrull, Isabel Fort-Gallifa, Fedra Luciano-Mateo, Noemí Cabré, Anna Hernández-Aguilera, Jorge Joven, and Jordi Camps, “Metformin administration induces hepatotoxic effects in paraoxonase-1-deficient mice,” Chemico-Biological Interactions, 2016. View at Publisher · View at Google Scholar
  • Carlos Moya, and Salvador Máñez, “Paraoxonases: metabolic role and pharmacological projection,” Naunyn-Schmiedeberg's Archives of Pharmacology, 2018. View at Publisher · View at Google Scholar