Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B₁-Induced Experimental Hepatocellular Carcinoma

Table 3

Effect of TD on non enzymic antioxidants and thiols in serum of control and experimental animals.

Parameters	Group I (control)	Group II (AFB1 induced)	Group III (AFB1 induced + TD)	Group IV (TD alone)
Vitamin C	2.83±0.29	0.99±0.01^a∗	2.87±0.28^b∗	2.85±0.31^cNS
Vitamin E	2.43±0.28	1.09±0.19^a∗	2.38±0.27^b∗	2.45±0.26^cNS
Total thiols (TSHs)	5.16±0.59	3.07±0.39^a∗	5.09±0.51^b∗	5.17±0.53^cNS
Non protein thiols (NPSHs)	4.89±0.51	1.69±0.19^a∗	4.66±0.51^b∗	4.97±0.52^cNS
Reduced glutathione (GSH)	24.68±2.92	9.45±1.67^a∗	23.35±3.16^b∗	24.63±2.67^cNS

Units: GSH mg/100 g tissue, Vitamins C and E mg/dL tissue, TSH and NPSH: μg/mg protein. Values are expressed as mean ± SD for six animals. Comparisons are made between “a” Group II versus Group I, “b” Group III versus Group II, “c” Group IV versus Group I. The symbol *represents the statistical significance at 𝑃<0.05. NS: nonsignificant.