A Crucial Role of Bone Morphogenetic Protein Signaling in the Wound Healing Response in Acute Liver Injury Induced by Carbon Tetrachloride
Figure 4
Gene expressions in the CCl4-injured liver of BMPR1A-KO mice. (a) RT-PCR was performed in duplicate with total RNA from CCl4-injured livers of mice infected with mock, Ad-LacZ or Ad-Cre. Short size PCR products in BMPR1A (arrowhead in top panel) shows the deletion in BMPR1A mRNA generated by Cre recombination. (b) Real-time RT-PCR of Id1, albumin, and Tdo2. Relative expression was shown by ratio of albumin expression levels normalized by β-actin internal control to the value in 0-time of CCl4-treated liver. All data are shown as the means ± SE from three independent experiments. *, significant difference by Student’s -test.
