Enhanced Antitumor Activity with Combining Effect of mTOR Inhibition and Microtubule Stabilization in Hepatocellular Carcinoma
Figure 2
Patupilone inhibited proliferation in HCC cell lines. (a) Dose-dependent inhibition of HCC cell proliferation by patupilone. The effect of patupilone on cell viability was assessed by MTT assay. Dose-response curves of everolimus for all HCC cell lines were shown. Similar results were observed in 3 independent experiments. (b) Average IC50 values of patupilone in HCC cell lines. Cumulative results from 3 independent experiments were shown as mean ± SEM.
