Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation

Figure 3

Immunohistological assessment by TUNEL. (a) Laparotomy with saline: TUNEL, ×100. (b) SOLT with saline: TUNEL, ×100. (c) SOLT with GABAR agonist: TUNEL, ×100. (d) Ratio of TUNEL-positive nuclei. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). GABAR, γ-aminobutyric acid receptor; HV, hepatic vein; SFSG, small-for-size graft; SOLT, split orthotopic liver transplantation; PV, portal vein; and TUNEL, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling.

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