Table 2: Baseline characteristics and treatment response in 141 patients treated with peginterferon plus ribavirin according to IFNL4 ss469415590 variant.

IFNL4 major, IFNL4 minor, values (major versus minor groups)

Gender, male/female46/4725/230.900
Age, years56.1 ± 11.754.7 ± 10.60.488
Previous treatment: naïve/relapse/null68/19/629/7/120.0042
AST, IU/L53.4 ± 48.565.0 ± 44.00.167
ALT, IU/L65.1 ± 64.982.0 ± 63.30.14
γ-GTP, IU/L40.9 ± 39.287.5 ± 98.90.000107
Hemoglobin, g/dL13.9 ± 1.214.2 ± 1.20.16
Platelets, ×104/mm316.8 ± 5.716.8 ± 6.11.00
Treatment response
 RVR, 1500.0079
 EVR, 595<0.0001
 SVR/relapse/null60/23/1010/12/25<0.0001

Null: null response; AST: aspirate aminotransferase; ALT: alanine aminotransferase; γ-GTP: γ-glutamyltransferase; RVR: rapid virological response; EVR: early virological response; SVR: sustained virological response.