What Are the Precursor and Early Lesions of Peripheral Intrahepatic Cholangiocarcinoma?

Table 1

Main clinicopathologic features of the cases studied.

	Peripheral ICC	Perihilar CC	HCC	cHC-CC
Number of cases	37	34	25	18
Age (years)	65±1.8	61±1.7	62±2.1	63±1.8
Sex (male/female)*	21/16	19/15	17/8	14/4
Hepatitis virus*
HBsAg (+)	6	1	9	6
HCV (+)	7	3	13	6
HBsAg (+)/HCV (+)	0	0	0	1
HBsAg (−)/HCV (−)	24	30	3	6
Cirrhosis*	4	1	25	11
Tumor size*
Φ>3 cm	31	20	10	8
Φ≦3 cm	6	11	15	9

∗Number of cases. CC: cholangiocarcinoma; ICC: intrahepatic CC; HCC: hepatocellular carcinoma; cHC-CC: combined hepatocellular cholangiocarcinoma.