International Journal of Hepatology / 2018 / Article / Tab 4

Research Article

Prevalence and Determinants of Significant Liver Fibrosis by Vibration-Controlled Transient Elastography in Thai Chronic Hepatitis B Patients

Table 4

Multivariable logistic regression analysis on factors associated with significant fibrosis (F2-4).

VariableCrude OR (95CI)P-valueAdjusted OR (95CI)P-value

Gender (Ref=female)3.48(1.81-6.68)<0.0013.24(1.36-7.72)0.008
Body mass index (kg/m2)1.12(1.03-1.21)0.0061.03(0.92-1.14)0.650
Diabetes mellitus3.71(1.35-10.18)0.0112.32(0.72-7.49)0.160
AST (Ref=≤1 x ULN)10.68(4.72-24.20)<0.0015.71(2.03-16.04)0.001
ALT (Ref=≤1 x ULN)6.33(3.15-12.72)<0.0011.90(0.75-4.84)0.178
ALP (U/L)1.02(1.01-1.03)0.0041.01(1.00-1.02)0.520
Hemoglobin (g/dL)1.24(1.00-1.54)0.0460.97(0.72-1.29)0.825

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ULN: Upper limit of normal;
ALP: Alkaline phosphatase; OR: Odds ratio; 95%CI: Confidence interval 95%.