Diastolic Dysfunction Is a Predictor of Poor Survival in Patients with Decompensated Cirrhosis
Table 5
Cox regression model for predicting survival in patients with decompensated cirrhosis.
Univariate analysis
Multivariate analysis
Hazard ratio
95% CI
value
Hazard ratio
95% CI
value
Age
0.97
0.97-1.03
0.17
Male sex
0.6
0.18-1.98
0.4
Hemoglobin (g/dl)
0.72
0.48-1.04
0.11
Albumin (g/dl)
0.11
0.05-0.33
0.001
0.32
0.14-0.7
0.005
MELD
1.05
1.01-1.16
0.01
Child-Pugh class
1.52
1.2-1.94
0.01
Presence of ascites
2.02
1.14-4.16
0.05
1.33
0.59-2.96
0.48
Alcohol vs. other etiology
1.72
0.8-3.6
0.72
LVEF (%)
1.02
0.96-1.08
0.27
presence of LVDD
4.19
1.78-9.88
0.001
2.72
1.07-6.9
0.03
Alcohol vs. other etiology
1.72
0.8-3.6
0.72
Abbreviations: LVDD: left ventricular diastolic dysfunction; MELD: model for end-stage liver disease; LVEF: left ventricle ejection fraction; ratio: ratio of early diastolic annular velocity to peak early diastolic annular wave velocity.
