Increased Nitric Oxide and Attenuated Diastolic Blood Pressure Variability in African Americans with Mildly Impaired Renal Function
Table 1
Clinical and renal characteristics of normal or mildly impaired renal function groups.
Normal renal function
Mildly impaired renal function
Variable
GFR > 90 mL/min per 1.73 m2 ()
GFR 60–89 mL/min per 1.73 m2 ()
Clinical characteristics
#Normotensive/pre-hypertensive
7/15 (32%/64%)
7/9 (44%/56%)
#Male/female
2/20 (9%/90%)
3/13 (19%/81%)
#Med. taper/no Meds
5/17 (23%/77%)
9/7 (56%/46%)
Age (years)
51.0 ± 1.4
54.1 ± 1.5
BMI (kg/m2)
33.0 ± 1.0
30.0 ± 1.3
Total fat free mass (kg)
51.8 ± 1.4
51.1 ± 2.7
Total fat mass (kg)
38.9 ± 2.2
33.4 ± 2.9
Total cholesterol (mg/dL)
189.3 ± 6.1
202.6 ± 6.2
LDL cholesterol (mg/dL)
111.1 ± 6.7
119.1 ± 6.5
HDL cholesterol (mg/dL)
61.7 ± 3.8
66.0 ± 4.1
Triglycerides (mg/dL)
82.3 ± 6.6
87.4 ± 8.1
Fasting glucose (mg/dL)
95.2 ± 2.1
94.5 ± 2.4
Renal characteristics
Urine total volume (mL)
1708.8 ± 160.8
1853.3 ± 267.6
Urinary Na+ (mmol/gCr)
93.1 ± 7.6
91.8 ± 10.1
Urinary creatinine (g/24hr)
1.5 ± 0.1
1.5 ± 0.1
Urinary albumin (mg/24hr)
8.9 ± 0.8
8.2 ± 1.0
Serum creatinine (mg/dL)
0.8 ± 0.02
1.0 ± 0.03*
GFR (mL/min per 1.73 m2)
105.8 ± 2.1
78.6 ± 2.2*
Values are expressed as means ± SEM. BMI, body mass index; GFR, glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
*Denotes significant difference between groups; .
