Research Article
An NOS3 Haplotype Is Protective against Hypertension in a Caucasian Population
Table 1
Clinical characteristics of cases and controls.
| | Cases () | Controls () | P-value |
| | Age (years) | 63.9 (9.4) | 40.8 (18.3) | .05 | | Males, n (%) | 125 (54.4) | 68 (22.2) | .05 | | BMI | 28.7 (4.1) | 27.5 (4.4) | .05 | | Smokers, n (%) | 84 (36.5) | 80 (29.9) | | | SBP (mmHg) | 145.3 (15.7) | 124.4 (12.3) | .05 | | DBP (mmHg) | 85.1 (10.2) | 68.8 (9.7) | .05 | | PP (mmHg) | 59.3 (17.2) | 57.1 (14.1) | | | CAD, n (%) | 65 (28.3) | — | N/A | | Creatinine (mg/dL) | 1.09 (0.8) | 0.92 (0.9) | .05 | | Urea (mg/dL) | 40.8 (8.6) | 36.5 (6.6) | .05 | | Potassium (mmol/L) | 4.3 (0.5) | 4.4 (0.3) | .26 | | Sodium (mmol/L) | 138.4 (3.1) | 140.0 (4.5) | .38 | | Total Cholesterol (mg/dL) | 190.88 (48.4) | — | N/A | | LDL Cholesterol (mg/dL) | 113.7 (39.5) | — | N/A | | HDL Cholesterol (mg/dL) | 46.9 (17.8) | — | N/A | | Triglycerides (mg/dL) | 132.4 (64.5) | — | N/A | | Drug treatment (%) | 89.6 | — | N/A | | ACE-inhibitors (%) | 45.2 | — | N/A | | ARBs (%) | 29.0 | — | N/A | | Beta-blockers (%) | 50.3 | — | N/A | | CCBs (%) | 36.8 | — | N/A | | Diuretics (%) | 50.9 | — | N/A | | Nitrates (%) | 13.5 | — | N/A | | Statins (%) | 39.7 | — | N/A |
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Values are mean (standard deviation), unless otherwise specified. Abbreviations: BMI = body mass index, SBP = systolic blood pressure, DBP = diastolic blood pressure, PP = pulse pressure, CAD = coronary artery disease, LDL = low-density lipoprotein, HDL = high density lipoprotein, ACE = angiotensin converting enzyme, ARBs = angiotensin receptor blockers, CCBs = calcium channel blockers, N/A = nonapplicable.
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