The Age-Dependent Contribution of Aortic Incident and Reflected Pressure Waves to Central Blood Pressure in African-Americans

Table 1

Clinical and hemodynamic characteristics of the study population.

	≤50 years (𝑛=289)	>50 years (𝑛=611)
Variable	Mean ± SD	Mean ± SD	𝑃 value
Age (years)	38±9	67±10	<0.001
Males (%)	41	36	0.15
Weight (kg)	81.8±21	79±18	0.07
Height (m)	1.69±0.10	1.67±0.10	0.004
SBP (mmHg)	125±21	139±22.8	<0.001
DBP (mmHg)	78±14	79±13	0.201
PP (mmHg)	47±13	60±19	<0.001
MAP (mmHg)	93±15	99±14	<0.001
CSBP (mmHg)	112±20	127±22	<0.001
CDP (mmHg)	79±14	81±12	0.15
CPP (mmHg)	33±11	47±17	<0.001
CMAP (mmHg)	90±15	96±10𝑥020444	<0.001
HR (beats/min)	74±14	69±12	<0.001
ED (ms)	303±37	308±35	0.07
AP (mmHg)	6±7	14±9	<0.001
P1 (mmHg)	27±7	33±12	<0.001
Tr (ms)	144±17	135±15	<0.001
AI75 (%)	16±14	25±11	<0.001
AI (%)	16±16	28±12	<0.001
PWV (m/sec)	8.7±1.6	9.2±1.9	0.001
PPA	1.45±0.2	1.30±0.2	<0.001
Brachial-central SBP (mmHg)	13±6	12±7	0.028
Brachial-central PP (mmHg)	14±6	12±6	0.011
ΔTr (ms)	159±37	174±35	<0.001
HTN (%)	35	75	<0.001
Chol (%)	16	47	<0.001
DM (%)	13	38	<0.001
CAD (%)	8	21	<0.001

Abbreviations: SBP: systolic blood pressure, DBP: diastolic blood pressure, PP: pulse pressure, MAP: mean arterial pressure, HR: heart rate, ED: ejection duration, AP: augmented pressure, P1: incident pressure, Tr: round trip travel time, AI: augmentation index, AI@75: heart rate-corrected augmentation index, PWV: pulse wave velocity, PPA: pulse pressure amplification, ΔTr: reflected wave systolic duration, HTN: hypertension, Chol: hypercholesterolemia, DM: diabetes mellitus, CAD: coronary artery disease, kg: kilograms, mmHg: millimeters of mercury, ms: milliseconds, m: meters, m/sec: meters per second.