Review Article

Adrenocortical Causes of Hypertension

Table 1

Endocrine causes of hypertension.

Adrenal dependent

(1) Pheochromocytoma
(2) Cushing’s syndrome
(3) Primary hyperaldosteronism
(4) Other adrenocortical tumors (i.e., carcinoma, other)
(5) Genetic defects affecting adrenocortical function
    (i) Congenital adrenal hyperplasia: 11β-Hydroxylase and 17α-Hydroxylase deficiency, primarily
    (ii) Primary cortisol resistance

Apparent mineralocorticoid excess (AME)/11β-Hydroxysteroid dehydrogenase deficiency
   (i) Type 1 AME
  (ii) Type 2 AME
   (i) Licorice or carbenoxolone ingestion (type 1 AME)
    (ii) Cushing’s syndrome (type 2 AME)

 Thyroid dependent

  Parathyroid dependent

  Pituitary dependent
   (1) Acromegaly
   (2) Cushing’s disease