Risk Factors Related to Low Ankle-Brachial Index Measured by Traditional and Modified Definition in Hypertensive Elderly Patients

Table 2

Clinical and laboratorial characteristics of the groups with normal (>0.9) and low (≤0.9) ankle-brachial index (ABI) obtained by AHA/TASC II standardization and by modified definition.

Characteristic	AHA definition			Modified definition
	ABI > 0.9; (𝑛=53)	ABI ≤ 0.9; (𝑛=12)	𝑃 value	ABI > 0.9; (𝑛=44)	ABI ≤ 0.9; (𝑛=21)	𝑃 value
Age, years	73.5±0.8	72.1±1.3	NS	73.4±0.9	72.9±1.1	NS
Body mass index, kg/m^2	27.1±0.6	27.5±1.6	NS	26.7±0.7	28.0±1.0	NS
Waist circumference, cm	92.3±1.9	94.7±3.6	NS	91.3±2.0	95.6±2.6	NS
Metabolic syndrome, 𝑛 (%)	22 (41%)	9 (75%)	<0.05	17 (38%)	14 (67%)	<0.05
CV diseases, 𝑛 (%)^†	5 (9%)	7 (58%)	<0.001	3 (6%)	9 (42%)	<0.001
Diabetes, 𝑛 (%)	7 (13%)	10 (83%)	<0.01	9 (20%)	6 (29%)	<0.05
Smoker, 𝑛 (%)	11 (21%)	4 (33%)	NS	9 (20%)	6 (29%)	<0.05
Cardiovascular risk
(i) FRS ≥ 20%, 𝑛 (%)	20 (38%)	12 (100%)	<0.001	16 (36%)	18 (86%)	<0.001
(ii) FRS < 20%, 𝑛 (%)	33 (62%)	0 (0%)	<0.001	28 (63%)	3 (14%)	<0.001
LV hypertrophy, 𝑛 (%)	13 (24%)	5 (41%)	NS	10 (23%)	8 (38%)	NS
GFR, mL/min/1.73 m^2	68±3	66±10	NS	69±3	68±6	NS
Fasting glucose, mg/dL	94±3.5	139±3.0	<0.05	98±2	120±9	<0.05
Total cholesterol, mg/dL	211±5	227±17	NS	209±6	223±10	NS
LDL-cholesterol, mg/dL	130±5	146±20	NS	124±5	154±13	<0.05
HDL-cholesterol, mg/dL	53±2	42±2	<0.05	54±2	43±2	0.01
Triglycerides, mg/dL	139±10	167±24	NS	141±11	151±16	NS
Uric acid, mg/dL	5.5±0.2	5.2±0.4	NS	5.6±0.2	5.3±0.3	NS
ABI, arbitrary units	1.07±0.01	0.81±0.02	<0.01	1.08±0.01	0.75±0.03	<0.001

Data are expressed as mean ± SEM or 𝑛 (%) when indicated. ABI: ankle-brachial index; CV: cardiovascular; FRS: Framingham risk score; LV: left ventricular; GFR: glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein; NS: nonsignificant. ^†Include coronary heart disease: stroke, or transitory ischemic accident.