Review Article

Upregulation of the Renin-Angiotensin-Aldosterone-Ouabain System in the Brain Is the Core Mechanism in the Genesis of All Types of Hypertension

Figure 4

A supposed cascade of genesis of hypertension and acting sites of antihypertensive agents. In fact, when we treated hypertensive patients with these agents, reflex tachycardia is missing. This means that these antihypertensive agents are resetting the blood pressure regulatory center to a lower level besides their original actions such as vasodilation and diuresis.
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