Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice
Figure 1
ACE2 activity is increased in the stromal vascular fraction (SVF) isolated from visceral adipose tissue of HF-fed C57BL/6 mice. ACE2 activity was quantified in mouse peritoneal macrophages (MPMs), bone marrow (BM), and SVF isolated from epididymal (EF), retroperitoneal (RPF) or subcutaneous (SubQ) adipose tissue from LF or HF-fed mice. Data are mean ± SEM from 3-4 mice/diet group. *: compared to LF.
