International Journal of Hypertension / 2013 / Article / Tab 5

Research Article

Serum Cotinine Levels and Prehypertension in Never Smokers

Table 5

Association between serum cotinine levels and prehypertension by body mass index.

Serum cotinine quartilesNo. at riskCasesAge-, sex-adjusted odds ratio
(95% CI)
Multivariable-adjusted odds ratio
(95% CI)*

BMI < 30 kg/m2
 Quartile 1 (≤0.024 ng/mL)3501051 (referent)1 (referent)
 Quartile 2 (0.025–0.054 ng/mL)3551201.37 (0.98, 1.90)1.38 (1.01, 1.89)
 Quartile 3 (0.055–0.223 ng/mL)3261061.79 (1.14, 2.81)1.79 (1.13, 2.83)
 Quartile 4 (≥0.224 ng/mL)3251141.65 (1.07, 2.54)1.66 (1.08, 2.55)
P trend0.01630.0167
BMI ≥ 30 kg/m2
 Quartile 1 (≤0.024 ng/mL)138601 (Referent)1 (Referent)
 Quartile 2 (0.025–0.054 ng/mL)169680.85 (0.56, 1.29)0.86 (0.57, 1.30)
 Quartile 3 (0.055–0.223 ng/mL)182790.83 (0.48, 1.43)0.84 (0.48, 1.47)
 Quartile 4 (≥0.224 ng/mL)182821.07 (0.57, 2.00)1.05 (0.53, 2.10)
P trend0.81760.8858

*Adjusted for age (years), sex (men, women), ethnicity (non-Hispanic white, non-Hispanic black, Mexican Americans, others), education categories (<high school, high school, >high school), drinking (never drinker, former drinker, 1or 2 drink/day, ≥3 drinks/day), glycohemoglobin (%), total cholesterol (mg/dL), below poverty level (%), and hormone use (ever, never).
P-interaction of cotinine quartiles and obese = 0.3751.