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International Journal of Hypertension
Volume 2013, Article ID 513214, 6 pages
Review Article

Renal Denervation for Treating Resistant Hypertension: Current Evidence and Future Insights from a Global Perspective

1Facultad de Medicina, Universidad de Ciencias Médicas “Dr. Serafín Ruiz de Zárate Ruiz”, Santa Clara, 50100 Villa Clara, Cuba
2Southern Illinois University School of Medicine and Prairie Education and Research Cooperative, Springfield, IL 62701, USA

Received 29 August 2013; Revised 14 October 2013; Accepted 18 October 2013

Academic Editor: Kazushi Tsuda

Copyright © 2013 Y. Castro Torres and Richard E. Katholi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Adequate blood pressure control represents an important goal for all physicians due to the complications of hypertension which reduce patients' quality of life. A new interventional strategy to reduce blood pressure has been developed for patients with resistant hypertension. Catheter-based renal denervation has demonstrated excellent results in recent investigations associated with few side effects. With the growing diffusion of this technique worldwide, some medical societies have published consensus statements to guide physicians how to best apply this procedure. Questions remain to be answered such as the long-term durability of renal denervation, the efficacy in patients with other sympathetically mediated diseases, and whether renal denervation would benefit patients with stage 1 hypertension.