Research Article
Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans
Table 3
Biochemical, hormonal, and echocardiographic characteristics of the subjects according to aldosterone concentration tertiles.
| Variable | Tertile 1 | Tertile 2 | Tertile 3 | value
| (<231 pmol·L−1) | (231–276 pmol·L−1) | (>276 pmol·L−1) | () | ) | () |
| Plasma aldosterone (pmol·L−1) | 187.6 (28.70) | 255.5 (11.41) | 315.0 (37.63) | 0.0000 | Plasma renin (ng·mL−1) | 19.3 (4.313) | 21.6 (5.453) | 26.2 (9.674) | 0.0032 | ARR | 10.1 (2.242) | 12.5 (3.019) | 13.7 (6.228) | 0.0002 | Age (yrs) | 49.3 (10.72) | 49.9 (11.53) | 48.0 (11.10) | 0.7492 | Body mass index | 26.3 (4.971) | 27.4 (4.349) | 26.3 (5.136) | 0.5103 | Plasma sodium (mmol·L−1) | 138.4 (7.598) | 136.3 (6.929) | 137.9 (8.173) | 0.3514 | Plasma potassium (mmol·L−1) | 4.25 (0.747) | 3.87 (0.804) | 3.98 (0.798) | 0.0974 | LV internal diameter (diastole) | 4.71 (0.406) | 4.76 (0.485) | 4.76 (0.489) | 0.8697 | LV posterior wall thickness (cm) | 1.13 (0.159) | 1.13 (0.191) | 1.14 (0.187) | 0.8970 | IV septal thickness (cm) | 1.05 (0.184) | 1.09 (0.219) | 1.02 (0.203) | 0.2265 | Relative wall thickness | 0.48 (0.085) | 0.48 (0.092) | 0.48 (0.082) | 0.7365 | LV mass index (g·m−2.7) | 47.1 (9.217) | 50.9 (14.59) | 47.8 (15.85) | 0.3036 | Systolic blood pressure (mmHg) | 154.1 (21.57) | 145.8 (24.15) | 152.4 (23.40) | 0.1871 | Diastolic blood pressure (mmHg) | 91.5 (11.86) | 85.7 (12.28) | 87.5 (10.93) | 0.0948 | Left atrial diameter (cm) | 3.87 (0.421) | 3.78 (0.513) | 3.89 (0.604) | 0.5749 | LV geometry | | | | | Normal geometry (%) | 22.2 | 27.9 | 27.3 | | Concentric remodelling (%) | 55.6 | 37.2 | 45.5 | 0.5945 | Eccentric hypertrophy (%) | 11.1 | 14.0 | 6.8 | | Concentric hypertrophy (%) | 11.1 | 20.9 | 20.4 | |
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ARR: aldosterone-to-renin ratio; LV: left ventricular; IV: interventricular.
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