Review Article
Elevated Blood Pressure in the Acute Phase of Stroke and the Role of Angiotensin Receptor Blockers
| Study | Year | Study design | Antihypertensive agent |
| Acute Candesartan Cilexetil Therapy in Stroke Survivors (ACCESS) [27] | 2003 | Prospective, double-blind, placebo-controlled, randomized, multicenter phase II study. | Candesartan cilexitil | Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) [28]* | 2008 | Prospective, double-blind, placebo-controlled, randomized, multicenter phase III study. | Telmisartan | The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST) [29] | 2011 | Prospective, double-blind, placebo-controlled, randomized, multicenter phase III study. | Candesartan cilexitil |
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In the PRoFESS trial a subgroup analysis has been considered.
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