Review Article

Elevated Blood Pressure in the Acute Phase of Stroke and the Role of Angiotensin Receptor Blockers

Table 1

Included trials.

StudyYearStudy designAntihypertensive agent

Acute Candesartan Cilexetil Therapy in Stroke Survivors (ACCESS) [27]2003Prospective, double-blind, placebo-controlled, randomized, multicenter phase II study.Candesartan cilexitil
Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) [28]*2008Prospective, double-blind, placebo-controlled, randomized, multicenter phase III study.Telmisartan
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST) [29]2011Prospective, double-blind, placebo-controlled, randomized, multicenter phase III study.Candesartan cilexitil

In the PRoFESS trial a subgroup analysis has been considered.