Interleukin-2/Anti-Interleukin-2 Immune Complex Expands Regulatory T Cells and Reduces Angiotensin II-Induced Aortic Stiffening
Figure 5
IL-2/ administration inhibits Ang II-induced immune activation in splenic tissues. Splenic lymphocytes were isolated and stimulated with PMA, ionomycin, and Brefeldin A and stained for surface markers and intracellular cytokines. The lymphocytes were gated on the CD4+ population. The mean percentage of CD4+ T cells producing IFN-γ (a) and IL-17a (b) is shown. per group. Data are means ± SEM.
