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International Journal of Hypertension
Volume 2015, Article ID 139465, 12 pages
Clinical Study

Blood Pressure Response to Zofenopril or Irbesartan Each Combined with Hydrochlorothiazide in High-Risk Hypertensives Uncontrolled by Monotherapy: A Randomized, Double-Blind, Controlled, Parallel Group, Noninferiority Trial

1L. Sacco Hospital, 20157 Milano, Italy
2Italian Institute of Telemedicine, Solbiate Arno, 21048 Varese, Italy
3Istituto Auxologico Italiano and University of Milano-Bicocca, 20149 Milano, Italy

Received 15 April 2015; Revised 25 June 2015; Accepted 2 July 2015

Academic Editor: Francesco Cappuccio

Copyright © 2015 Ettore Malacco et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [4 citations]

The following is the list of published articles that have cited the current article.

  • Claudio Napoli, Stefano Omboni, and Claudio Borghi, “Fixed-dose combination of zofenopril plus hydrochlorothiazide vs. irbesartan plus hydrochlorothiazide in hypertensive patients with established metabolic syndrome uncontrolled by previous monotherapy. The ZAMES study (Zofenopril in Advanced MEtabolic Syndrome),” Journal of Hypertension, vol. 34, no. 11, pp. 2287–2297, 2016. View at Publisher · View at Google Scholar
  • Stefano Omboni, Ettore Malacco, Claudio Napoli, Pietro Amedeo Modesti, Athanasios Manolis, Gianfranco Parati, Enrico Agabiti-Rosei, and Claudio Borghi, “Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized “Z” Studies,” Advances in Therapy, 2017. View at Publisher · View at Google Scholar
  • I. T. Murkamilov, I. S. Sabirov, V. V. Fomin, and F. A. Yusupov, “Endothelial dysfunction and arterial wall stiffness: New targets in diabetic nephropathy,” Terapevticheskii arkhiv, vol. 89, no. 10, pp. 87, 2017. View at Publisher · View at Google Scholar
  • Chrisa Dimou, Christina Antza, Evangelos Akrivos, Ioannis Doundoulakis, Stella Stabouli, Anna Bettina Haidich, and Vasilios Kotsis, “A systematic review and network meta-analysis of the comparative efficacy of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in hypertension,” Journal of Human Hypertension, 2018. View at Publisher · View at Google Scholar