Blood Pressure Response to Zofenopril or Irbesartan Each Combined with Hydrochlorothiazide in High-Risk Hypertensives Uncontrolled by Monotherapy: A Randomized, Double-Blind, Controlled, Parallel Group, Noninferiority Trial
Table 1
Demographic and clinical data of the patients of the intention-to-treat population at the time of randomization (). Data are separately shown for the two groups of randomization and reported as mean (±SD) or absolute () and relative frequency (%). BMI: Body Mass Index; LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; CV: cardiovascular; SBP: systolic blood pressure; DBP: diastolic blood pressure.
Zofenopril 30–60 mg + HCTZ 12.5 mg
Irbesartan 150–300 mg + HCTZ 12.5 mg
value
()
()
Age (years, mean ± SD)
56 ± 11
56 ± 11
0.926
Males (, %)
124 (58)
120 (54)
0.411
BMI (kg/m2, mean ± SD)
27 ± 3
27 ± 3
0.415
Waist circumference (cm, mean ± SD)
98 ± 10
98 ± 10
0.674
Age at first diagnosis of hypertension (years, mean ± SD)
