Clinical Study
Blood Pressure Response to Zofenopril or Irbesartan Each Combined with Hydrochlorothiazide in High-Risk Hypertensives Uncontrolled by Monotherapy: A Randomized, Double-Blind, Controlled, Parallel Group, Noninferiority Trial
Table 4
Rate of office blood pressure (BP) responders (<140/90 mmHg in nondiabetics and <130/80 mmHg in diabetics or high-risk patients, or SBP reduction ≥20 mmHg or DBP reduction ≥10 mmHg) and baseline-adjusted office and 24-hour SBP and DBP reductions after 48 weeks of treatment with zofenopril 60 mg + hydrochlorothiazide (HCTZ) or irbesartan 300 mg + HCTZ. Data are shown for the intention-to-treat population and reported as absolute () and relative (%) frequencies and as mean and 95% confidence interval. The value refers to the statistical significance of the intertreatment difference.
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