Review Article

Implications of Renal Denervation Therapy in Patients with Sleep Apnea

Table 1

Major clinical studies carried out in patients with AHS syndrome undergoing RND therapy. Modified by Shantha and Pancholy [24].

AuthorYearPatients ()OSA patientsAHI pre-RDNAHI post-RDN (6 months)

Damascelli et al. [25]201324 RHT patients 263.326.5
Schmiedel et al. [26]201340 RHT patients 162517
Thakur et al. [27]201321 RHT patients 621.110.5
Witkowski et al. [28]201110 RHT patients,
all with OSA
10
10
30.716.1
Zhao et al. [29]201331 RHT patients 153227

Resistant hypertension = RHT; obstructive sleep apnea = OSA; apnea-hypopnea index = AHI; renal sympathetic denervation = RDN; apnea-hypopnea sleep syndrome = AHS.